Cell death in the mammalian blastocyst.

  title={Cell death in the mammalian blastocyst.},
  author={Kate Hardy},
  journal={Molecular human reproduction},
  volume={3 10},
  • Kate Hardy
  • Published 1997 in Molecular human reproduction
Cell death is a widespread feature in the blastocysts of many mammals. Isolated cells in both the inner cell mass and the trophectoderm undergo cell death. These dying cells appear morphologically to be undergoing apoptosis. In mouse blastocysts, a wave of cell death is seen in vivo, suggesting that it plays an important role in normal development. However, cell death is increased under suboptimal culture conditions. There is evidence that levels of cell death are regulated by 'survival… CONTINUE READING
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