Cell death in early neural development: beyond the neurotrophic theory.

  title={Cell death in early neural development: beyond the neurotrophic theory.},
  author={Enrique J de la Rosa and Flora de Pablo},
  journal={Trends in neurosciences},
  volume={23 10},
The important effect of cell death on projecting neurons during development is well established. However, this mainstream research might have diverted recognition of the cell death that occurs at earlier stages of neural development, affecting proliferating neural precursor cells and young neuroblasts. In this article, we briefly present observations supporting the occurrence of programmed cell death during early neural development in a regulated fashion that to some extent parallels the death… CONTINUE READING

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