Cell death in Pseudomonas aeruginosa biofilm development.

@article{Webb2003CellDI,
  title={Cell death in Pseudomonas aeruginosa biofilm development.},
  author={J. Webb and L. Thompson and S. James and T. Charlton and T. Tolker-Nielsen and B. Koch and M. Givskov and S. Kjelleberg},
  journal={Journal of bacteriology},
  year={2003},
  volume={185 15},
  pages={
          4585-92
        }
}
Bacteria growing in biofilms often develop multicellular, three-dimensional structures known as microcolonies. Complex differentiation within biofilms of Pseudomonas aeruginosa occurs, leading to the creation of voids inside microcolonies and to the dispersal of cells from within these voids. However, key developmental processes regulating these events are poorly understood. A normal component of multicellular development is cell death. Here we report that a repeatable pattern of cell death and… Expand
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