Cell death by overload of the elastin-laminin receptor on human activated lymphocytes: protection by lactose and melibiose.

@article{Pterszegi1999CellDB,
  title={Cell death by overload of the elastin-laminin receptor on human activated lymphocytes: protection by lactose and melibiose.},
  author={G P{\'e}terszegi and St{\'e}phanie Texier and Ladislas Robert},
  journal={European journal of clinical investigation},
  year={1999},
  volume={29 2},
  pages={166-72}
}
BACKGROUND Activated human lymphocytes were shown to express the elastin-laminin receptor in vitro and also in vivo in atherosclerotic plaques. In the presence of the agonist, elastin peptides, this receptor was shown to mediate an increased cell proliferation and an increased synthesis and excretion of an elastase-type serine endopeptidase. In this study, we investigated the variation of the above reaction as a function of agonist concentration. MATERIALS AND METHODS Human lymphocytes were… CONTINUE READING
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