Cell death by apoptosis during involution of the lactating breast in mice and rats.

@article{Walker1989CellDB,
  title={Cell death by apoptosis during involution of the lactating breast in mice and rats.},
  author={Neal I. Walker and R E Bennett and John F. R. Kerr},
  journal={The American journal of anatomy},
  year={1989},
  volume={185 1},
  pages={
          19-32
        }
}
The role of cell death in involution of lactating breast was investigated in mice and rats by light and electron microscopy. Apoptosis, recognized by sharply demarcated compaction of chromatin against the nuclear envelope and by shrinkage and budding of the whole cell to form membrane-bounded apoptotic bodies, was responsible for major loss of cells in both species. In the mouse, rapid involution during the first 2 days was associated with shedding of large numbers of apoptotic bodies derived… 
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