Cell death and survival through the endoplasmic reticulum-mitochondrial axis.

@article{BravoSagua2012CellDA,
  title={Cell death and survival through the endoplasmic reticulum-mitochondrial axis.},
  author={Roberto Bravo-Sagua and Andrea Estefan{\'i}a Peralta Rodr{\'i}guez and Jovan Kuzmicic and Toni Gutierrez and Camila Lopez-Crisosto and Castiblanco Quiroga and Jessica D{\'i}az-Elizondo and Mario Chiong and Thomas G. Gillette and Beverly A Rothermel and Sergio Lavandero},
  journal={Current molecular medicine},
  year={2012},
  volume={13 2},
  pages={
          317-29
        }
}
The endoplasmic reticulum has a central role in biosynthesis of a variety of proteins and lipids. Mitochondria generate ATP, synthesize and process numerous metabolites, and are key regulators of cell death. The architectures of endoplasmic reticulum and mitochondria change continually via the process of membrane fusion, fission, elongation, degradation, and renewal. These structural changes correlate with important changes in organellar function. Both organelles are capable of moving along the… CONTINUE READING
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