Cell cycle regulation of a T-type calcium current in early mouse embryos

@article{Day1998CellCR,
  title={Cell cycle regulation of a T-type calcium current in early mouse embryos},
  author={Margot Day and Martin J. Johnson and David I. Cook},
  journal={Pfl{\"u}gers Archiv},
  year={1998},
  volume={436},
  pages={834-842}
}
 In this paper we report that the amplitude of the T-current changes in a cell cycle-dependent manner in single- and two-cell embryos, being large in unfertilized oocytes and decreasing after fertilization throughout the first cell cycle to a minimum in early M phase, before increasing again during late telophase. This increase can be prevented by arresting the cell cycle in metaphase, but is not prevented by cytochalasin D. During the second cell cycle the T-current remains large until late G2… CONTINUE READING
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