Cell cycle regulation in human embryonic stem cells: links to adaptation to cell culture

@article{Brta2013CellCR,
  title={Cell cycle regulation in human embryonic stem cells: links to adaptation to cell culture},
  author={Tom{\'a}{\vs} B{\'a}rta and D. Dole{\vz}alov{\'a} and Z. Holubcov{\'a} and A. Hampl},
  journal={Experimental Biology and Medicine},
  year={2013},
  volume={238},
  pages={271 - 275}
}
Cell cycle represents not only a tightly orchestrated mechanism of cell replication and cell division but it also plays an important role in regulation of cell fate decision. Particularly in the context of pluripotent stem cells or multipotent progenitor cells, regulation of cell fate decision is of paramount importance. It has been shown that human embryonic stem cells (hESCs) show unique cell cycle characteristics, such as short doubling time due to abbreviated G1 phase; these properties… Expand
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