Cell-cycle mechanisms involved in podocyte proliferation in cellular lesion of focal segmental glomerulosclerosis.

@article{Wang2004CellcycleMI,
  title={Cell-cycle mechanisms involved in podocyte proliferation in cellular lesion of focal segmental glomerulosclerosis.},
  author={Suxia Wang and Ji Hoon Kim and Kyung Chul Moon and Hye Kyoung Hong and Hyun Soon Lee},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2004},
  volume={43 1},
  pages={19-27}
}
BACKGROUND Podocyte injury may induce podocyte proliferation, which results in glomerular scarring. The cellular lesion, seen in some patients with primary focal segmental glomerulosclerosis (FSGS), is characterized by proliferation of cells covering the sclerotic or collapsed glomerular tufts. Cell-cycle mechanisms by which podocyte proliferation occurs in the cellular lesion of FSGS are unclear. METHODS We examined expression patterns of cyclin D1; cyclin E; cyclin A; cyclin B1; cyclin… CONTINUE READING