Cell cycle kinetics, tissue transglutaminase and programmed cell death (apoptosis).

@article{Alaoui1992CellCK,
  title={Cell cycle kinetics, tissue transglutaminase and programmed cell death (apoptosis).},
  author={Sa{\"i}d El Alaoui and Shahzad Mian and John Lawry and G{\'e}rard Quash and Martin Griffin},
  journal={FEBS letters},
  year={1992},
  volume={311 2},
  pages={174-8}
}
Studies were undertaken on a highly metastatic hamster fibrosarcoma cell line with a view to assessing whether cells entering into apoptosis, measured by counting the number of transglutaminase mediated detergent insoluble envelopes, has any synchrony with a particular phase of the cell cycle. A double exposure of thymidine was used to block cells in early S-phase. Flow cytometry in combination with [3H]thymidine incorporation into DNA was used to assess the degree of synchrony and progression… CONTINUE READING

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