Cell-cycle control during meiotic maturation.

@article{Kishimoto2003CellcycleCD,
  title={Cell-cycle control during meiotic maturation.},
  author={Toshifumi Kishimoto},
  journal={Current opinion in cell biology},
  year={2003},
  volume={15 6},
  pages={
          654-63
        }
}
The meiotic cell cycle, which is comprised of two consecutive M-phases, is crucial for the production of haploid germ cells. Although both mitotic and meiotic M-phases share cyclin-B-Cdc2/CDK1 as a key controller, there are meiosis-specific modulations in the regulation of cyclin-B-Cdc2. Recent insights indicate that a common pattern in these modulations can be found by considering the particular activities of mitogen-activated protein kinase (MAPK) during meiosis. The G(2)-phase arrest of… CONTINUE READING
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