Cell cycle and proliferation dynamics of adult rat oligodendrocytes.

  title={Cell cycle and proliferation dynamics of adult rat oligodendrocytes.},
  author={Rodolfo Vick and James M. Collins and George H Devries},
  journal={Journal of neuroscience research},
  volume={33 1},
Adult oligodendrocytes (OLGs) have been shown to be mitotically responsive when co-cultured with dorsal root ganglion. We have investigated the population dynamics of the OLG proliferative response, including the maximum percent of cells which will proliferate and the cell cycle duration time of the adult rat OLG. Adult OLGs were stimulated with pituitary extract and either continuously labeled or pulse labeled with bromodeoxyuridine (BrdU). The labeled cells were stained with a fluorescent… CONTINUE READING