Cell cycle and melanoma--two different tumours from the same cell type.

@article{Cree2000CellCA,
  title={Cell cycle and melanoma--two different tumours from the same cell type.},
  author={Ian A Cree},
  journal={The Journal of pathology},
  year={2000},
  volume={191 2},
  pages={112-4}
}
  • Ian A Cree
  • Published 2000 in The Journal of pathology
Melanoma of the uvea of the eye and melanoma of the skin share a common cell of origin, but differ substantially in their behaviour and response to chemotherapy. There is increasing evidence that this is related to differences in their molecular phenotype, particularly in relation to the expression of cell cycle-associated proteins. Since many cytotoxic agents act by damaging DNA, resistance is often associated with intact mechanisms which allow the neoplastic cells to arrest their growth while… CONTINUE READING
Highly Cited
This paper has 23 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…