Cell cycle and cell size dependence of susceptibility to hydrodynamic forces.

@article{AlRubeai1995CellCA,
  title={Cell cycle and cell size dependence of susceptibility to hydrodynamic forces.},
  author={Mohamed Al-Rubeai and Rashim Pal Singh and A. Nicholas Emery and Zengmin Zhang},
  journal={Biotechnology and bioengineering},
  year={1995},
  volume={46 1},
  pages={88-92}
}
Exposure of animal cells to intense hydrodynamic forces exerted in turbulent capillary flow, and by controiled agitation and aeration, resulted in preferential destruction of S and G(2) cells and the extent of destruction of these cells was dependent upon the intensity of the action. The loss of these cells was possibly due to their larger size. However, the appearance of large numbers of membrane-bound vesicular structures similar to apoptotic bodies as well as cells with low DNA stainability… CONTINUE READING

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