Cell cycle analysis of proliferative zone chondrocytes in growth plates elongating at different rates.

@article{Wilsman1996CellCA,
  title={Cell cycle analysis of proliferative zone chondrocytes in growth plates elongating at different rates.},
  author={Norman J. Wilsman and Cornelia E. Farnum and Eric M. Green and E M Lieferman and Murray K. Clayton},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={1996},
  volume={14 4},
  pages={562-72}
}
Regulation of postnatal growth of long bones occurs in multiple levels of chondrocytic activity, including stem cell proliferation, proliferative zone cycling, and regulation of changes in chondrocytic shape during hypertrophy. The differentiation sequence of chondrocytes is the same in all growth plates, but rates of elongation at a single point in time and over a period of time differ widely among individual growth plates, which suggests that the rates of sequential gene activation and… CONTINUE READING
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