Cell culture plastics with immobilized interleukin-4 for monocyte differentiation.


Standard cell culture plastic was surface modified by passive adsorption or covalent attachment of interleukin (IL)-4 and investigated for its ability to induce differentiation of human monocytes into mature dendritic cells, a process dose-dependently regulated by IL-4. Covalent attachment of IL-4 proceeded via anthraquinone photochemistry to introduce… (More)
DOI: 10.1002/jbm.a.32986