Cell culture medium composition and translational adult bone marrow-derived stem cell research.

@article{Sotiropoulou2006CellCM,
  title={Cell culture medium composition and translational adult bone marrow-derived stem cell research.},
  author={Panagiota A. Sotiropoulou and Sonia Cristina Gualtieri de Andrade Perez and Maria L. Salagianni and Constantin N. Baxevanis and Michael Papamichail},
  journal={Stem cells},
  year={2006},
  volume={24 5},
  pages={1409-10}
}
The use of fetal calf serum (FCS) for the culture of cells to be used in clinical trials raises potential hazards that cannot be neglected, but this is a regulatory issue. However, as specifically regards the isolation and expansion of human mesenchymal stem cells (MSCs), unfortunately serum-free media have not yet been defined. The alternative of using autologous serum is feasible only for the minority of clinical protocols involving low numbers of MSCs, because a minimum concentration of 10… CONTINUE READING

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