Cell culture and animal studies for intracerebral delivery of borocaptate in liposomal formulation.

Abstract

The efficacy of a liposomal formulation for intracerebral delivery of borocaptate (BSH) to brain tumor cells has been investigated using cell culture to study BSH uptake and persistence and using tumor-bearing rats to determine BSH distribution in the brain. During a 16-hr incubation, cellular uptake of BSH solution or BSH liposomal formulation was similar… (More)

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Cite this paper

@article{Ji2001CellCA, title={Cell culture and animal studies for intracerebral delivery of borocaptate in liposomal formulation.}, author={Bingqing Ji and W Chen and Daniel R. Lu and David S Halpern}, journal={Drug delivery}, year={2001}, volume={8 1}, pages={13-7} }