Cell communication across gap junctions: a historical perspective and current developments.

  title={Cell communication across gap junctions: a historical perspective and current developments.},
  author={W. H. Evans},
  journal={Biochemical Society transactions},
  volume={43 3},
Collaborative communication lies at the centre of multicellular life. Gap junctions (GJs) are surface membrane structures that allow direct communication between cells. They were discovered in the 1960s following the convergence of the detection of low-resistance electrical interactions between cells and anatomical studies of intercellular contact points. GJs purified from liver plasma membranes contained a 27 kDa protein constituent; it was later named Cx32 (connexin 32) after its full… CONTINUE READING


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