Cell-cell signaling in co-cultures of macrophages and fibroblasts.


The foreign body response (FBR) comprises a general, ubiquitous host tissue-based reaction to implanted materials. In vitro cell-based models are frequently employed to study FBR mechanisms involving cell signaling responses to materials. However, these models often study only one cell type, identify only limited signals, and cannot accurately represent the… (More)
DOI: 10.1016/j.biomaterials.2010.07.101


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