Cell-cell communication in the osteoblast/osteocyte lineage.

  title={Cell-cell communication in the osteoblast/osteocyte lineage.},
  author={Roberto Civitelli},
  journal={Archives of biochemistry and biophysics},
  volume={473 2},
Skeletal development (bone modeling) and its maintenance in post-natal life in response to local and systemic stimuli (bone remodeling) require coordinated activity among osteoblasts (bone forming cells), osteocytes (cells embedded in bone) and osteoclasts (bone resorbing cells), in order to meet the needs of structural integrity, mechanical competence and maintenance of mineral homeostasis. One mechanism of cell-cell interaction is via direct cell-cell communication via gap junctions. These… CONTINUE READING


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