Cell biology: Ageing nucleus gets out of shape

@article{Lans2006CellBA,
  title={Cell biology: Ageing nucleus gets out of shape},
  author={H. Lans and J. Hoeijmakers},
  journal={Nature},
  year={2006},
  volume={440},
  pages={32-34}
}
In certain premature-ageing syndromes, the architecture of the cell nucleus is abnormal. An animal model shows similar malformations during normal ageing, corroborating the idea that genome instability underlies ageing. 
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