Cell-based therapy in the repair of osteochondral defects: a novel use for adipose tissue.

@article{Nathan2003CellbasedTI,
  title={Cell-based therapy in the repair of osteochondral defects: a novel use for adipose tissue.},
  author={S. Shanmuganathan Nathan and Shamal Das De and Ashvin Thambyah and Chen Fen and James Choh-Hong Goh and Eng Hin Lee},
  journal={Tissue engineering},
  year={2003},
  volume={9 4},
  pages={733-44}
}
Mesenchymal stem cells are currently procured from periosteum and bone marrow. The procurement of stem cells from these sources is tedious and gives a low yield of cells. This study was aimed at circumventing these problems and allowing for a method that would be more acceptable in the clinical setting. Tissue for transplantation was harvested from a single New Zealand White rabbit. Cells were more readily obtained from adipose tissue than from bone marrow or periosteum. The present method also… CONTINUE READING

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