Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis.

@article{Parker1999CellautonomousAN,
  title={Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis.},
  author={Leon H. Parker and Didier Y. R. Stainier},
  journal={Development},
  year={1999},
  volume={126 12},
  pages={2643-51}
}
Vertebrate embryonic hematopoiesis is a complex process that involves a number of cellular interactions, notably those occurring between endothelial and blood cells. The zebrafish cloche mutation affects both the hematopoietic and endothelial lineages from an early stage (Stainier, D. Y. R., Weinstein, B. M., Detrich, H. W. R., Zon, L. I. and Fishman, M. C. (1995) Development 121, 3141-3150). cloche mutants lack endocardium, as well as head and trunk endothelium, and nearly all blood cells… CONTINUE READING

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