Cell attachment properties and infectivity of host-adapted and environmentally adapted Citrobacter rodentium.

@article{Bishop2007CellAP,
  title={Cell attachment properties and infectivity of host-adapted and environmentally adapted Citrobacter rodentium.},
  author={Anne L. Bishop and Siouxsie Wiles and Gordon Dougan and Gad Frankel},
  journal={Microbes and infection},
  year={2007},
  volume={9 11},
  pages={1316-24}
}
Citrobacter rodentium belongs to a family of extracellular enteric pathogens that include enterohaemorrhagic and enteropathogenic Escherichia coli, which colonises the gastrointestinal mucosa by the attaching and effacing (A/E) mechanism. We previously described the appearance of a 'hyper-infectious' state after passage of C. rodentium through the murine gastrointestinal tract. Here we report that host-adapted C. rodentium is able to efficiently adhere and trigger actin polymerisation on… CONTINUE READING

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