Cell adhesion, cellular tension, and cell cycle control.

@article{Klein2007CellAC,
  title={Cell adhesion, cellular tension, and cell cycle control.},
  author={Eric A Klein and Yuval Yung and Paola Castagnino and Devashish Kothapalli and Richard K. Assoian},
  journal={Methods in enzymology},
  year={2007},
  volume={426},
  pages={155-75}
}
Cooperative signaling between growth factor receptor tyrosine kinases, integrins, and the actin cytoskeleton is required for activation of the G1-phase cyclin-dependent kinases and progression through G1-phase. Increasing evidence suggests that there is cell type specificity in these cooperative interactions and that the compliance of the underlying substratum can strongly affect adhesion-dependent signaling to the cell cycle. This chapter reviews our current methods for studying how cell type… CONTINUE READING

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