Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.

@article{Toyohara2015CellTU,
  title={Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.},
  author={Takafumi Toyohara and Shin-ichi Mae and Shin-Ichi Sueta and Tatsuyuki Inoue and Yukiko Yamagishi and Tatsuya Kawamoto and Tomoko Kasahara and Azusa Hoshina and Taro Toyoda and Hiromi Tanaka and Toshikazu Araoka and Aiko Sato-Otsubo and Kazutoshi Takahashi and Yasunori Sato and Noboru Yamaji and Seishi Ogawa and Shinya Yamanaka and Kenji Osafune},
  journal={Stem cells translational medicine},
  year={2015},
  volume={4 9},
  pages={980-92}
}
UNLABELLED Acute kidney injury (AKI) is defined as a rapid loss of renal function resulting from various etiologies, with a mortality rate exceeding 60% among intensive care patients. Because conventional treatments have failed to alleviate this condition, the development of regenerative therapies using human induced pluripotent stem cells (hiPSCs) presents a promising new therapeutic option for AKI. We describe our methodology for generating renal progenitors from hiPSCs that show potential in… CONTINUE READING
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