Cell Surface Expression of 1 D-Adrenergic Receptors Is Controlled by Heterodimerization with 1 B-Adrenergic Receptors *

@inproceedings{Hague2004CellSE,
  title={Cell Surface Expression of 1 D-Adrenergic Receptors Is Controlled by Heterodimerization with 1 B-Adrenergic Receptors *},
  author={Chris Hague and Michelle A. Uberti and Zhongjian Chen and Randy A Hall and Kenneth P. Minneman},
  year={2004}
}
1-Adrenergic receptors (ARs) belong to the large Class I G protein-coupled receptor superfamily and comprise three subtypes ( 1A, 1B, and 1D). Previous work with heterologously expressed C-terminal green fluorescent protein (GFP)-tagged 1-ARs showed that 1Aand 1B-ARs localize to the plasma membrane, whereas 1D-ARs accumulate intracellularly. We recently showed that 1Dand 1B-ARs form heterodimers, whereas 1Dand 1A-ARs do not. Here, we examined the role of heterodimerization in regulating 1D-AR… CONTINUE READING
33 Citations
1 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.

Heterodimerization Controls 1D-AR Surface Expression

  • M. Margeta-Mitrovic, Y. N. Jan, L. Y. Jan
  • Proc. Natl. Acad. Sci
  • 2001

Similar Papers

Loading similar papers…