Cell Polarity: Quantitative Modeling as a Tool in Cell Biology

  title={Cell Polarity: Quantitative Modeling as a Tool in Cell Biology},
  author={Alex Mogilner and Jun Allard and Roy Wollman},
  pages={175 - 179}
Among a number of innovative approaches that have modernized cell biology, modeling has a prominent yet unusual place. One popular view is that we progress linearly, from conceptual to ever more detailed models. We review recent discoveries of cell polarity mechanisms, in which modeling played an important role, to demonstrate that the experiment-theory feedback loop requires diverse models characterized by varying levels of biological detail and mathematical complexity. We argue that a… 

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