Cell Origins and Diagnostic Accuracy of Interleukin 27 in Pleural Effusions

  title={Cell Origins and Diagnostic Accuracy of Interleukin 27 in Pleural Effusions},
  author={Wei-Bing Yang and Qiu-li Liang and Zhi-Jian Ye and Chun-Mi Niu and Wan-Li Ma and Xian-zhi Xiong and Rong-hui Du and Qiong Zhou and Jian-chu Zhang and Huan-zhong Shi},
  booktitle={PloS one},
The objective of the present study was to investigate the presence of interleukin (IL)-27 in pleural effusions and to evaluate the diagnostic significance of pleural IL-27. The concentrations of IL-27 were determined in pleural fluids and sera from 68 patients with tuberculous pleural effusion, 63 malignant pleural effusion, 22 infectious pleural effusion, and 21 transudative pleural effusion. Flow cytometry was used to identify which pleural cell types expressed IL-27. It was found that the… CONTINUE READING
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