Cell Lines Expression Caused by Histone Deacetylation in Lung Cancer Receptor Type II β Unresponsiveness and Loss of TGF-β Heterogeneous Transforming Growth Factor ( TGF )-Updated

@inproceedings{Osada2001CellLE,
  title={Cell Lines Expression Caused by Histone Deacetylation in Lung Cancer Receptor Type II β Unresponsiveness and Loss of TGF-β Heterogeneous Transforming Growth Factor ( TGF )-Updated},
  author={Hirotaka Osada and Yoshio Tatematsu and Akira Masuda and Toshiko Saito and Miyabi Sugiyama and Kiyoshi Yanagisawa and Takashi Takahashi},
  year={2001}
}
Transforming growth factor (TGF)strongly inhibits epithelial cell proliferation. Alterations of TGFsignaling are thought to play a role in tumorigenesis. We show in the present study that most lung cancer cell lines have lost the growth-inhibitory response to TGFsignal, and that those with TGFunresponsiveness can be divided into two major groups, TGFtype II… CONTINUE READING