Cell-Free Urinary MicroRNA-99a and MicroRNA-125b Are Diagnostic Markers for the Non-Invasive Screening of Bladder Cancer

@inproceedings{Zhang2014CellFreeUM,
  title={Cell-Free Urinary MicroRNA-99a and MicroRNA-125b Are Diagnostic Markers for the Non-Invasive Screening of Bladder Cancer},
  author={Ding-Zuan Zhang and K. -F Lau and Eddie Shu-yin Chan and Guanghui Wang and C. W. Szeto and Kenneth E Wong and Richard Kwong Wai Choy and Chi-fai Ng},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Evidence implicated the diagnostic significance of microRNAs in whole urine/urine sediments in urothelial carcinoma of the bladder (UCB). However, the contaminated blood cells in patients with haematouria significantly altered the expression profiles of urinary microRNA, influencing the test accuracy. METHODS MicroRNA profiles of the urine supernatants of UCB patients and controls without any malignancy and profiles of malignant and corresponding normal mucosa tissues from the… CONTINUE READING

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