• DOI:10.1371/journal.pone.0043268
Corpus ID: 2872291

Cell-Free MicroRNA Expression Profiles in Malignant Effusion Associated with Patient Survival in Non-Small Cell Lung Cancer

@article{Wang2012CellFreeME,
  title={Cell-Free MicroRNA Expression Profiles in Malignant Effusion Associated with Patient Survival in Non-Small Cell Lung Cancer},
  author={T. Wang and M. Lv and S. Shen and Sheng Zhou and P. Wang and Yueqiu Chen and Baorui Liu and Li-ke Yu and Y. Hou},
  journal={PLoS ONE},
  year={2012},
  volume={7}
}

• T. Wang, M. Lv, +6 authors Y. Hou
• Published 2012
• Medicine
• PLoS ONE

Objective MicroRNAs (miRNAs) expression is altered in cancer cells, and miRNAs could serve as diagnostic and prognostic biomarker for cancer patients. This study was designed to analyze circulating miRNAs expression in the malignant pleural effusion (MPE) and their association with patient survival in non-small cell lung cancer (NSCLC). Methods Pleural effusion from 184 patients with NSCLC and MPE were collected. MiRNA microarray and bioinformatics interpretation were used to evaluate miRNA… Expand