Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

Abstract

The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational output, but how this influences transcriptional statistics from… (More)
DOI: 10.1371/journal.pcbi.1003161

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Cite this paper

@inproceedings{Zopf2013CellCycleDO, title={Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression}, author={C. J. Zopf and Katie Quinn and Joshua Zeidman and Narendra Maheshri}, booktitle={PLoS Computational Biology}, year={2013} }