Cell Cycle: Who Turns the Crank?

@article{Tyson2011CellCW,
  title={Cell Cycle: Who Turns the Crank?},
  author={John J. Tyson and B{\'e}la Nov{\'a}k},
  journal={Current Biology},
  year={2011},
  volume={21},
  pages={R185-R187}
}
The oscillating activity of a single CDK-cyclin fusion protein can drive the orderly progression of yeast cells through DNA replication, mitosis and cell division.