Cell Cycle: Sustained ERK Signalling Represses the Inhibitors

@article{Sharrocks2006CellCS,
  title={Cell Cycle: Sustained ERK Signalling Represses the Inhibitors},
  author={Andrew D Sharrocks},
  journal={Current Biology},
  year={2006},
  volume={16},
  pages={R540-R542}
}
The duration of ERK pathway signalling determines the proliferative response of cells. A recent study has shown that cell cycle re-entry requires the downregulation of an anti-proliferative gene cluster following sustained activation of the ERK pathway.