Cell Adhesion-Mediated Radioresistance (CAM-RR) Extracellular Matrix-Dependent Improvement of Cell Survival in Human Tumor and Normal Cells in Vitro

@article{Cordes2003CellAR,
  title={Cell Adhesion-Mediated Radioresistance (CAM-RR) Extracellular Matrix-Dependent Improvement of Cell Survival in Human Tumor and Normal Cells in Vitro},
  author={Nils Cordes and Viktor Meineke},
  journal={Strahlentherapie und Onkologie},
  year={2003},
  volume={179},
  pages={337-344}
}
Cell-extracellular matrix (ECM) contact is thought to have great impact on cellular mechanisms resulting in increased cell survival upon exposure to ionizing radiation. Several human tumor cell lines and normal human fibroblastic cell strains of different origin, all of them expressing the wide-spread and important integrin subunit β1, were irradiated, and clonogenic cell survival, β1-integrin cell surface expression, and adhesive functionality were investigated. Material and Methods: Human… CONTINUE READING

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Ionizing radiation modulates integrin expression in a normal human dermal fibroblast stem cell model in vitro – the role of beta1-integrins in the radiation reaction of the skin

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