Cell–cell interactions at the ectoplasmic specialization in the testis

  title={Cell–cell interactions at the ectoplasmic specialization in the testis},
  author={Dolores D. Mruk and C. Yan Cheng},
  journal={Trends in Endocrinology & Metabolism},
During spermatogenesis, the movement of developing germ cells across the seminiferous epithelium involves the restructuring of adherens junctions that form between Sertoli cells and between Sertoli and germ cells such as the ectoplasmic specialization (ES). At the ultrastructural level, the ES has been thoroughly studied for the past three decades. Until recently, however, relatively little has been known about the molecular architecture, not to mention the mechanism, that regulates the ES… CONTINUE READING
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