Cell‐Surface Carbohydrates in Cell Recognition and Response

@article{Brandley1986CellSurfaceCI,
  title={Cell‐Surface Carbohydrates in Cell Recognition and Response},
  author={Brian K. Brandley and Ronald L. Schnaar},
  journal={Journal of Leukocyte Biology},
  year={1986},
  volume={40}
}
Complex carbohydrates coat the surfaces of cells and have the potential to carry the information necessary for cell–cell recognition. Sugar‐specific receptors (lectins) are also present on cells, and can interact with sugars on apposing cells. This may result in the adhesion of the two cells via carbohydrates and specific cell‐surface receptors. Such carbohydrate‐directed cell adhesion appears to be important in many intercellular activities including infection by bacteria and viruses… 

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  • D. Weir
  • Biology
    FEMS microbiology immunology
  • 1989
The way in which carbohydrate based recognition has been shown to be involved and may provide the basis for further understanding of the importance of these molecules in host-parasite interaction is emphasized.

Quantitative Micro-Adhesion Assay on Polystyrene Matrices

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Labeled carbohydrates were proved to be a reliable tool for the study of cell surface composition and could be an alternative tool for taxonomic and physiological studies on microalgae or even on other groups of organisms.

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Revealing the carbohydrate pattern on a cell surface by super-resolution imaging.

This work employed direct stochastic optical reconstruction microscopy (dSTORM) to visualize the pattern of N-acetylglucosamine on Vero cell membranes at the nanometer level of resolution, and found that N-GlcNAcs exist in irregular clusters on the apical membrane.
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