Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization defects via extracellular transglutaminase 2

Abstract

We have recently found that celiac disease patient serum-derived autoantibodies targeted against transglutaminase 2 interfere with several steps of angiogenesis, including endothelial sprouting and migration, though the mechanism involved remained to be fully characterized. This study now investigated the processes underlying the antiangiogenic effects… (More)
DOI: 10.1007/s00018-013-1455-5

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@article{Nadalutti2013CeliacDP, title={Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization defects via extracellular transglutaminase 2}, author={Cristina Antonella Nadalutti and Ilma Rita Korponay-Szab{\'o} and Katri Kaukinen and Martin Griffin and Markku J M{\"a}ki and Katri Lindfors}, journal={Cellular and Molecular Life Sciences}, year={2013}, volume={71}, pages={1315-1326} }