Celiac Disease and Nonceliac Gluten Sensitivity: A Review

  title={Celiac Disease and Nonceliac Gluten Sensitivity: A Review},
  author={Maureen M. Leonard and Anna Sapone and Carlo Catassi and Alessio Fasano},
Importance The prevalence of gluten-related disorders is rising, and increasing numbers of individuals are empirically trying a gluten-free diet for a variety of signs and symptoms. This review aims to present current evidence regarding screening, diagnosis, and treatment for celiac disease and nonceliac gluten sensitivity. Observations Celiac disease is a gluten-induced immune-mediated enteropathy characterized by a specific genetic genotype (HLA-DQ2 and HLA-DQ8 genes) and autoantibodies… 

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