Celiac Disease and Its Role in the Development of Metabolic Bone Disease.

  title={Celiac Disease and Its Role in the Development of Metabolic Bone Disease.},
  author={Dejan Micic and Vijaya L Rao and Carol E. Semrad},
  journal={Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry},
  • D. MicicV. RaoC. Semrad
  • Published 1 April 2020
  • Medicine, Biology
  • Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Celiac disease and bone.

Standardized guidelines are needed to develop standardized guidelines for screening and treatment of metabolic bone disease in patients with CD to identify those who may need early intervention with prescription osteoporosis therapy.

Study of effect of gluten-free diet on vitamin D levels and bone mineral density in celiac disease patients

It is concluded that there is significant increase in vitamin D levels as well as Z-score, bone mass density (BMD) and bone Mass Content (BMC) after 6 months of GFD.

The Role of Cannabinoid Receptor Type 2 in the Bone Loss Associated With Pediatric Celiac Disease

CB2 could be a molecular marker to predict the risk of bone alterations in CD and a pharmacological target to reduce bone mass loss in patients who need a direct intervention on bone metabolism, in addition to the GFD.

Investigation of the Factors Affecting Bone Mineral Density in Children with Celiac Disease

There was no correlation among Marsh classification, presence of specific human leukocyte antigens, and low BMD in Iranian children with CD, and BMI can be a predictor of bone density in children withCD and may be applied clinically in early screenings to evaluate the bone health status in these children.

Treatment of cystic fibrosis related bone disease

How does a celiac iceberg really float? The relationship between celiac disease and gluten.

Celiac disease (CD) is an autoimmune intestinal disease caused by intolerance of genetically susceptible individuals after intake of gluten-containing grains (including wheat, barley, etc.) and their

Celiac disease: Definition, classification, historical and epistemological profiles, anatomopathological aspects, clinical signs, differential diagnosis, treatments and prognosis. Proposed diagnostic scheme for celiac disease (DSCNC)

The state of the art on celiac disease is not yet able to explain the precise aetiology and atypical forms of the disease, as well as the real impact of genetic predisposition on clinical manifestations.

Common clinical symptoms and concomitant disease in celiac patients – A large cohort study in the North-East of Iran

The classic type is common type of CD in northeast Iran, consequence screening for CD in cases whiteout classic symptoms (such as dyspepsia) is recommended in female CD patients in first visit.

Fracture risk assessment in celiac disease: a registry-based cohort study

Summary Celiac disease is associated with an increased fracture risk but is not a direct input to the FRAX® calculation. When celiac disease is considered as a secondary osteoporosis risk factor or

Normalization of Anti Tissue Trans-glutaminase Antibodies in Patients with Histologically Confirmed Celiac Disease: A Retrospective Analysis

Normalization of Anti Tissue Transglutaminase Antibodies in Patients with Histologically Confirmed Celiac Disease: A Retrospective Analysis is presented.



Bone Mass and Mineral Metabolism Alterations in Adult Celiac Disease: Pathophysiology and Clinical Approach

The pathophysiology of bone loss is correlated to clinical aspects, defining an alternative proposal of management for this condition and the indications of guidelines are still imperfect and debated.

Bone Loss in Celiac Disease Is Related to Secondary Hyperparathyroidism

Bone density is reduced in the peripheral skeleton in celiac disease and this deficit persists despite treatment with apparent normalization at axial skeletal sites, related to the presence of secondary hyperparathyroidism which should be sought in all patients with treated Celiac disease.

Improved Bone Microarchitecture in Patients With Celiac Disease After 3 Years on a Gluten‐Free Diet

  • M. ZanchettaA. F. Costa J. Bai
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2018

Coeliac disease

Effect of zoledronic acid on bone mineral density in patients of celiac disease: A prospective, randomized, pilot study

Administration of zoledronic acid was not found to be better than GFD alone in increasing B MD in CD patients with low BMD in this pilot study.

Imbalance of Osteoclastogenesis‐Regulating Factors in Patients With Celiac Disease

  • A. TarantaD. Fortunati M. Bianchi
  • Medicine, Biology
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2004
Celiac disease is an autoimmune disorder characterized by atrophy of the intestine villi triggered by ingestion of gluten in genetically susceptible individuals. The association between celiac

Identification of tissue transglutaminase as the autoantigen of celiac disease

Tissue transglutaminase is identified as the unknown endomysial autoantigen of celiac disease, and gliadin is a preferred substrate for this enzyme, giving rise to novel antigenic epitopes.

Celiac disease and bone fractures: a systematic review and meta-analysis.

It is suggested that clinically diagnosed celiac disease and bone fractures co-occur and that Celiac disease was associated with an increased risk of hip fractures as well as fractures in general.