Celecoxib pharmacogenetics and pediatric adenotonsillectomy: a double-blinded randomized controlled study

@inproceedings{Murto2015CelecoxibPA,
  title={Celecoxib pharmacogenetics and pediatric adenotonsillectomy: a double-blinded randomized controlled study},
  author={Kimmo Murto and Christine Lamontagne and Colleen McFaul and Johnna MacCormick and Kelly-Ann Ramakko and Mary Aglipay and david. rosen and Regis Vaillancourt},
  booktitle={Canadian Journal of Anesthesia/Journal canadien d'anesth{\'e}sie},
  year={2015}
}
BackgroundPediatric adenotonsillectomy (A&T) is associated with prolonged pain and functional limitation. Celecoxib is an effective analgesic in adult surgery patients; however, its analgesic efficacy on pain and functional recovery in pediatric A&T patients is unknown.MethodsDuring 2009-2012, children (age 2-18 yr) scheduled for elective A&T were enrolled in a single-centre double-blind randomized controlled trial. Study participants received either oral placebo or celecoxib 6 mg·kg−1… CONTINUE READING
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