Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs.

Abstract

Celecoxib is an NSAID that was developed as a selective inhibitor of COX-2 and approved by the FDA for the treatment of various forms of arthritis and the management of acute or chronic pain. In addition, it was more recently approved as an oral adjunct to prevent colon cancer development in patients with familial adenomatous polyposis and is presently… (More)
DOI: 10.1517/13543784.17.2.197

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