Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway

@inproceedings{Yu2015CelastrolIA,
  title={Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway},
  author={Xiaolong Yu and Xin Zhou and Changlin Fu and Qiang Wang and Tao Nie and Fan Li Yijun Zou and Runsheng Guo and Hucheng Liu and Bin Zhang and Min Dai},
  booktitle={Oncology reports},
  year={2015}
}
Celastrol is an active compound extracted from the root bark of Triptergium wilfordii Hook F., also known as ̔Thunder of God Vine̓. It is a well-known Chinese medicinal herb that was found to inhibit tumor cell growth and promote apoptosis in several tumor cell lines. However, research into its effects on osteosarcoma cell apoptosis is still extremely limited. The present study was undertaken to determine the effect of celastrol on viability and apoptosis of osteosarcoma cells and furthermore… CONTINUE READING
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