Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor combination.


Avibactam (formerly NXL104, AVE1330A) is a synthetic non-β-lactam, β-lactamase inhibitor that inhibits the activities of Ambler class A and C β-lactamases and some Ambler class D enzymes. This review summarizes the existing data published for ceftazidime-avibactam, including relevant chemistry, mechanisms of action and resistance, microbiology… (More)
DOI: 10.1007/s40265-013-0013-7


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