Cefoxitin activity against multiply antibiotic-resistance Klebsiella pneumoniae in vitro.

@article{Jackson1977CefoxitinAA,
  title={Cefoxitin activity against multiply antibiotic-resistance Klebsiella pneumoniae in vitro.},
  author={R T Jackson and Felix Thomas and Robert H. Alford},
  journal={Antimicrobial agents and chemotherapy},
  year={1977},
  volume={11 1},
  pages={84-7}
}
Due to the emergence of cephalothin- and gentamicin-resistant Klebsiella pneumoniae at this institution, we investigated the in vitro activity of two new cephalosporin compounds-cefoxitin and cefamandole. Whereas both drugs were active against cephalothin- and gentamicin-susceptible isolates of Klebsiella, only cefoxitin exhibited significant activity against cephalothin- and gentamicin-resistant isolates. Seventeen of 20 (85%) of the cephalothin- and gentamicin-resistant isolates were… CONTINUE READING