Cefditoren activity against nearly 1000 non-fastidious bacterial isolates and the development of in vitro susceptibility test methods.

  title={Cefditoren activity against nearly 1000 non-fastidious bacterial isolates and the development of in vitro susceptibility test methods.},
  author={R. N. Jones and Douglas J. Biedenbach and D. M. Johnson},
  journal={Diagnostic microbiology and infectious disease},
  volume={37 2},
Antibacterial Activity of Cefditoren Against Major Community-Acquired Respiratory Pathogens Recently Isolated in Italy
Cefditoren, due to its potent activity, is a new effective therapeutic option for the treatment of respiratory tract infections.
Cefditoren: In Vitro Activity Against Respiratory Pathogens and β-Lactamase Stability
Cefditoren was the most active agent overall in terms of its overall activity against Enterobacteriaceae, Haemophilus influenzae, and gram-positive pathogens, and was significantly more resistant to hydrolysis by β-lactamases than cefprozil, loracarbef, and penicillin.
Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients
Cefditoren exhibited enhanced in vitro activity against the most common uropathogens in the outpatient setting, representing an alternative oral treatment option in patients with risk factors for resistance to first-line antibiotics.
Activity of cefditoren against respiratory pathogens.
Multistep studies of cefditoren, co-amoxiclav and cefprozil did not select for resistant mutants after 50 subcultures, compared with cefuroxime and azithromycin, where resistant mutants were selected in two and nine strains, respectively.
Cefditoren Pivoxil
Cefditoren pivoxil dosage regimens were as effective as a 10-day course of either cefadroxil 500mg once daily or cefuroxime axetil 250mg twice daily in treating uncomplicated skin and skin structure infections, including those caused by S. aureus and S. pyogenes.


An in vitro characterization of cefditoren, a new oral cephalosporin.
Investigation of the effect of laboratory variables on the in vitro activity of cefditoren indicates that it will present no special problems when tested in the clinical setting against bacterial pathogens.
In vitro activity of a new cephalosporin ME-1206 compared with other agents.
In vitro and in vivo antibacterial activities of ME1207, a new oral cephalosporin
ME1206 showed a broad spectrum of activity against gram-positive and gram-negative bacteria and was more active than cefaclor, T-2525, and cefixime against Staphylococcus aureus and Staphyllococcus epidermidis and against various beta-lactamases.
Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci.
The MICs of RPR 106972, cefditoren, two new oxazolidinones, and other oral and parenteral agents for 203 penicillin-susceptible and -resistant pneumococci were determined.
Comparison of Agar Dilution, Microdilution, E-Test, and Disk Diffusion Methods for Testing Activity of Cefditoren againstStreptococcus pneumoniae
All three methods for testing the MIC of cefditoren showed excellent correlation and major discrepancies were found for both methods with a breakpoint of ≤1.0 μg/ml, and no discrepancies wereFindings showed that the susceptibility of pneumococci to cefDIToren by agar dilution and microdilution and E-test methods and disk diffusion methods, respectively, showed good correlation.
Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically : approved standard
This document describes standard broth dilution and microdilution and agar dilution techniques and includes a series of procedures to standardize the way the tests are performed, and the performance, applications, and limitations of the current CLSI-recommended methods are described.
National Committee for Clinical Laboratory Standards.
Many members of the Academy of Pediatrics seem to be generally unaware of the fact that your Academy has participated for ten years in a very interesting and valuable organization, the National