Cefazolin high-inoculum effect in methicillin-susceptible Staphylococcus aureus from South American hospitals.

@article{Rincon2013CefazolinHE,
  title={Cefazolin high-inoculum effect in methicillin-susceptible Staphylococcus aureus from South American hospitals.},
  author={Sandra L Rincon and J. Guadalupe Reyes and Lina Paola Carvajal and Natalia Rojas and Fabi{\'a}n Cort{\'e}s and Diana Panesso and M {\'A}ngeles Guzm{\'a}n and Jeannete Zurita and Javier A Adachi and Barbara E. Murray and Esteban C. Nannini and C{\'e}sar A. Arias},
  journal={The Journal of antimicrobial chemotherapy},
  year={2013},
  volume={68 12},
  pages={2773-8}
}
OBJECTIVES Clinical failures with cefazolin have been described in high-inoculum infections caused by methicillin-susceptible Staphylococcus aureus (MSSA) producing type A β-lactamase. We investigated the prevalence of the cefazolin inoculum effect (InE) in MSSA from South American hospitals, since cefazolin is used routinely against MSSA due to concerns about the in vivo efficacy of isoxazolyl penicillins. METHODS MSSA isolates were recovered from bloodstream (n = 296) and osteomyelitis (n… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 5 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort

European Journal of Clinical Microbiology & Infectious Diseases • 2016
View 3 Excerpts
Highly Influenced

Cefazolin versus anti-staphylococcal penicillins for treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a narrative review.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases • 2018
View 3 Excerpts

Similar Papers

Loading similar papers…