Cdk9 regulates neural differentiation and its expression correlates with the differentiation grade of neuroblastoma and PNET tumors.

@article{Falco2005Cdk9RN,
  title={Cdk9 regulates neural differentiation and its expression correlates with the differentiation grade of neuroblastoma and PNET tumors.},
  author={Giulia De Falco and Cristiana Bellan and Alessandro D'Amuri and Giuseppina Angeloni and Eleonora Leucci and Antonio Giordano and Lorenzo Leoncini},
  journal={Cancer biology & therapy},
  year={2005},
  volume={4 3},
  pages={277-81}
}
Cdk9 is a member of the Cdc2-like family of kinases. Its cyclin partners are members of the family of cyclin T (T1, T2a and T2b) and cyclin K. The Cdk9/Cyclin T complex appears to be involved in regulating several physiological processes. Recently, Cdk9 has been identified as a regulator of the differentiation program of several cell types, such as muscle cells, monocytes and lymphocytes, suggesting that it may have a function in controlling specific differentiative pathways. We analyzed… CONTINUE READING

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